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We are subject to the risk of additional litigation and regulatory proceedings or actions in connection with the restatement of prior period financial statements. We previously restated our previously issued financial statements for the fiscal years 2002 and 2003, including interim periods in 2003, and the first two quarters of 2004. We may in the future be subject to class action suits, other litigation or regulatory proceedings or actions arising in relation to the restatement of our prior period financial statements. Any expenses incurred in connection with such a potential litigation or regulatory proceeding or action not covered by available insurance or any adverse resolution of this potential litigation or regulatory proceeding or action could have a material adverse effect on our business, results of operations, cash flows and financial condition. Further, any litigation or regulatory proceeding or action may be time consuming, and it may distract our management from the conduct of our business. Management concluded that we did not have a sufficient number of finance and accounting resources performing supervisory review and monitoring activities as of year-end 2004 and, accordingly, that we did not maintain effective controls over that period-end financial reporting process. We cannot assure you that we will be able to remediate this material weakness and conclude that our internal control over financial reporting is effective as of the end of 2005 or that the material weakness will not result in material misstatements of our financial statements. Under the Sarbanes-Oxley Act of 2002 and the rules issued thereunder, management is required to conduct an evaluation of the effectiveness of our internal control over financial reporting as of each yearend. We are also required to include in our Annual Reports on Form 10-K a report on management's assessment of the effectiveness of our internal control over financial reporting. Our registered public accounting firm also issues an audit report on management's assessment and our internal control over financial reporting. Management concluded that, as a result of the loss of certain finance personnel, the challenges of hiring new personnel while a merger was pending and the resource requirements necessary to address the restatement of our financial statements, we did not have a sufficient number of finance and accounting resources performing supervisory review and monitoring activities as of the end of 2004. We are in the process of addressing this material weakness by actively recruiting additional managerial level finance and accounting resources. We cannot assure you that management will not identify one or more additional significant deficiencies or material weaknesses in our internal control over financial reporting during 2005, that the steps we take to address any significant deficiencies or material weaknesses will be successful, that a significant deficiency or material weakness will not result in material errors in our financial statements before it is remediated, that management will be able to complete its assessment of internal control over financial reporting in a timely fashion in 2005, or that management will be able to conclude on the basis of its evaluation that our internal control over financial reporting was effective as of the end of 2005. If sales of our major products or royalty payments to us decrease, our results of operations could be materially adversely affected. Altace, Skelaxin, Thrombin-JMI, Levoxyl, Sonata and royalty revenues for the last twelve months ended September 30, 2005 accounted for 29.3%, 21.0%, 13.0%, and 4.7% of our total revenues from continuing operations, respectively, or 80.3% in total. We believe that these sources of revenue may constitute a significant portion of our revenues for the foreseeable future. However, the agreements associated with some sources of royalty income may be terminated upon short notice and without cause, or may be subject to substantial competition in the near future. Accordingly, any factor adversely affecting sales of any of these products or products for which we receive royalty payments could have a material adverse effect on our business, financial condition, results of operations and cash flows. 51. 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Migrainous infarction should be considered in the differential diagnosis of acute hearing symptoms, including unilateral and bilateral hearing loss. Accepted for publication June 11, 2002. Author contributions: Study concept and design Drs Lee, Whitman, Lim, Yi, Ying, and Baloh acquisition of data Drs Lee, Whitman, and Baloh analysis and interpretation of data Drs Lee, Whitman, Cho, Ying, and Baloh drafting of the manuscript Drs Lee, Whitman, Lim, Yi, Ying, and Baloh critical revision of the manuscript for important intellectual content Drs Lee, Whitman, Cho, and Baloh administrative, technical, or material support Drs Lee, Yi, and Cho supervision Drs Lee, Whitman, Lim, Yi, Cho, Ying, and Baloh ; . Corresponding author and reprints: Gregory T. Whitman, MD, Department of Neurology, University of California, Irvine, Medical Center, Building 53, Room 203, 101 The City Drive South, Orange, CA 92868. 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